Panacea Pharmaceuticals Announces Appointment of Stephen N. Keith, MD, MSPH as President and Chief Operating Officer
June 28, 2006– Gaithersburg, Maryland – Panacea Pharmaceuticals,
Inc. today announced the appointment of Stephen N. Keith, MD,
MSPH as President and Chief Operating Officer. Dr. Keith will
have responsibility for directing the company’s therapeutic
product development efforts for cancer and stroke, clinical development
process for cancer diagnostics, as well as launching the cancer
diagnostic laboratory services.
“We are very pleased to add Stephen to the team at Panacea,”
commented Hossein Ghanbari, PhD, Chairman, CEO and Chief Scientific
Officer at Panacea Pharmaceuticals. “He brings a broad and
valuable set of experiences to Panacea, including capital fund
raising, clinical development, product commercialization in the
U.S. and foreign markets, regulatory affairs and business development.
Most importantly, Stephen has demonstrated exceptional leadership
in building life science companies.”
Prior to joining Panacea, Dr. Keith was a Senior Consultant with
the Biologics Consulting Group and a Managing Director with Glocap
Advisors LLC, a boutique investment bank. He was a General Partner
with Emerging Technology Partners, an early-stage life sciences
venture capital firm, from 2002 to 2003. Dr. Keith has held a
range of senior management positions in the pharmaceutical and
biotechnology industries. Just prior to joining ETP, he held the
position of President and Chief Operating Officer of Antex Biologics,
Inc. From 1995 to 2000, Dr. Keith served as Vice President, Marketing
and Sales at North American Vaccine, Inc. From 1990 to 1995, Dr.
Keith held various positions at Merck & Co., Inc. including
Senior Director, Health Care Delivery Policy in Corporate Public
Affairs; Senior Customer Manager in the U.S. Human Health Division;
and Senior Director, Health Strategies, in the Merck-Medco Managed
Care Division.
Dr. Keith received the M.D. degree from the University of Illinois
in 1977 and completed a three-year residency in Pediatrics at
the University of California, Los Angeles in 1980. From 1980 to
1982, he was a Robert Wood Johnson Foundation Clinical Scholar
at UCLA, during which time he received a Masters in Science in
Public Health. From 1982 to 1987, Dr. Keith served on the faculty
of the Charles Drew Medical School and the UCLA School of Medicine
in the Department of Pediatrics. From 1987 to 1990, he served
as a Health Policy Advisor to the U.S. Senate Committee on Labor
and Human Resources under Senator Edward M. Kennedy. Dr. Keith
is a Fellow of the Academy of Pediatrics and a Diplomate of the
American Board of Pediatrics.
“I am excited to join Panacea and to work with Dr. Ghanbari,
the Board of Directors, and the Company’s research and development
staff to advance our products toward commercialization,”
commented Dr. Keith. “Panacea’s therapeutic and diagnostic
cancer products have strong potential to significantly improve
outcomes among individuals with a broad range of cancers, including
liver, prostate and breast cancer, along with leukemias affecting
children and adults. And our lead neuroprotectant product candidate,
PAN-811, could represent a breakthrough in reducing paralysis,
memory loss and other devastating consequences of ischemic stroke.”
About Panacea’s Oncology Platform
Panacea is pursuing the development of antibodies directed against
human aspartyl (asparaginyl) Beta-hydroxylase (HAAH) as novel
agents for the treatment of cancer with liver cancer as its first
intended indication. The Company is exploring both naked anti-HAAH
antibodies, as well as antibody conjugates with various chemotherapeutic
agents as lead candidates. Panacea is also pursuing the development
of diagnostic products based on anti-HAAH antibodies. A proprietary
blood-based assay has shown high sensitivity and specificity in
the detection of a range of cancers and responsiveness to chemotherapy,
thus facilitating the diagnosis and therapeutic management of
disease. Initial targets for the HAAH diagnostic products include
prostate and liver cancers, along with tests to determine responsiveness
to a current therapy of choice in patients with chronic myelogenous
leukemia. Panacea anticipates the initiation of its diagnostic
testing services later in 2006.
About PAN-811
PAN-811 is a small-molecule that fully blocks hypoxic and ischemic
neuronal cell death at a dose of 1 micromolar in vitro
and reduces infarct volume by up to 59% in the middle cerebral
artery occlusion rat model of stroke. It manifests dual mechanistic
functions including both Ca2+-chelation and free radical-scavenging
(Jiang, Z-G., et al., “A multifunctional cytoprotective
agent that reduces neurodegeneration after ischemia,” PNAS,
Vol. 103, No. 5, 1581-1586, 2006). The toxicology and pharmacokinetics
of the drug candidate have been demonstrated, and it is currently
in Phase II clinical trials at the NIH for a cancer indication.
Panacea expects to begin in 2007 a Phase Ib human clinical trial
to assess PAN-811 as a treatment for transient ischemic stroke.
About Panacea Pharmaceuticals, Inc.
Panacea Pharmaceuticals, Inc. is a privately-held biopharmaceutical
company focused on the development and commercialization of therapeutics
and diagnostics for diseases with substantial, unmet clinical
needs. The Company’s product development strategy is based
on novel therapeutic agents and approaches for cancer treatment,
as well as acute and chronic neurodegenerative conditions, such
as hypoxia-induced neurological insult, Parkinson’s Disease,
and Alzheimer’s disease. Panacea has an extensive patent
portfolio covering its neurodegenerative and oncology technologies.
More information about the Company is available at http://www.PanaceaPharma.com.
Except for historical information presented in this press
release, matters discussed herein may constitute “forward-looking
statements” within the meaning of the Private Securities
Litigation Reform Act of 1995. Forward-looking statements are
based on the opinions and estimates of management only as of the
date of this release and are subject to certain risks and uncertainties
that could cause actual results to differ materially from any
future results, performance, or achievements expressed or implied
by such statements. Factors that might cause such a difference
include, but are not limited to, uncertainties related to our
access to capital, the progress, costs, and results of any clinical
trials undertaken by us, progress of our research and development
projects, and uncertainties related to whether our product candidates
would ultimately achieve commercial success. We do not undertake
any obligation to update publicly any forward-looking statement,
whether as a result of new information, future events, or otherwise
unless required by law.
Contact:
Panacea Pharmaceuticals, Inc.
Stephen N. Keith, MD, MSPH
President & COO
Phone 240-243-8010; FAX 240-465-0450
skeith@panaceapharma.com
|