BOARD OF DIRECTORS Hossein A. Ghanbari, PhD Kasra Ghanbari Mehdi Hatamian, PhD Diana Lady Dougan Keitaro Yoshida

MANAGEMENT Hossein A. Ghanbari, PhD Chairman, CEO & Chief Scientific Officer Stephen Keith, MD, MSPH President and Chief Operating Officer Christine Brauer, PhD Vice President of Regulatory Affairs Pamela Jo Harris, MD, FACP Vice President Clinical and Medical Affairs M. Elisa Lane, JD General Counsel Michael S. Lebowitz, PhD Director of Research Zhi-gang Jiang, MD, PhD, MSc Director, Neurodegenerative Diseases Shinji Takeichi Director of Business Development

ADVISORS Carl R. Merril, MD Frank E. Young, MD, PhD Roscoe Brady, MD, PhD Li Mao, MD

COLLABORATORS Jack R. Wands, MD K. Dane Wittrup, PhD